Colchicine promotes atherosclerotic plaque stability independently of inflammation
W. Li, A. Lin, M. Hutton, H. Dhaliwal, J. Nadel, J. Rodor, S. Tumanov, T. Örd, M. Hadden, M. Mokry, B. M. Mol, G. Pasterkamp, M. P. Padula, C. L. Geczy, Y. Ramaswamy, , A. Misra
This study shows colchicine stabilizes atherosclerotic plaques by converting harmful SMC-derived cells into protective myofibroblast-like cells, independent of its anti-inflammatory effects.
bioRxiv · Oct 3, 2023 · PreprintCell Biology