Author

M. J. Pitcher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Spencer· 4 shared M. Bemark· 3 shared P. Dhami· 3 shared T. J. Tull· 3 shared D. D'Cruz· 2 shared J. H. Siu· 2 shared L. Montorsi· 2 shared M. Kleeman· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

J. Spencer

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Author profile →

4 papers

Recent·Most cited

Unanticipated interacting features of human gut-associated lymphoid tissues link microbiota, intestinal immunity and autoimmunity

L. Montorsi, M. J. Pitcher, Y. Zhao, A. Demonti, T. J. Tull, C. Dionisi, P. Dhami, R. J. Ellis, C. Bishop, J. Sanderson, S. Jain, D. D'Cruz, D. Gibbons, T. H. Winkler, M. Bemark, , J. Spencer

The paper identifies DN2 B cells in human GALT that interact with DC expressing DNASE1L3 and C1Q, linking microbiota, immunity, and autoimmunity.

bioRxiv · Aug 29, 2023Immunology

ChAdOx1 nCoV-19 (AZD1222) vaccine elicits monoclonal antibodies with potent cross-neutralizing activity against SARS-CoV-2 viral variants

J. Seow, C. Graham, S. R. Hallett, T. Lechmere, T. J. A. Maguire, I. Huettner, D. Cox, R. Roberts, A. Waters, C. C. Ward, C. Mant, M. J. Pitcher, J. Spencer, J. Fox, M. H. Malim, K. J. Doores

This study isolates monoclonal antibodies from a vaccinated individual and shows they neutralize multiple SARS-CoV-2 variants effectively.

bioRxiv · Sep 27, 2021Immunology

Two subsets of human marginal zone B cells resolved by global analysis of lymphoid tissues and blood

J. H. Siu, M. J. Pitcher, T. J. Tull, W. Guesdon, L. Montorsi, C. Armitage, K. T. Mahbubani, R. Ellis, P. Dhami, K. Todd, U. D. Kadolsky, M. Kleeman, D. P. D'Cruz, K. Saeb-Parsy, M. Bemark, , J. Spencer

The paper identifies two distinct subsets of human marginal zone B cells through global analysis of lymphoid tissues and blood, revealing differences in their biology and distribution.

bioRxiv · Mar 19, 2021Immunology

Human marginal zone B cell development from early T2 progenitors

T. J. Tull, M. J. Pitcher, W. Guesdon, J. H. Siu, C. Lebrero-Fernandez, Y. Zhao, N. Petrov, S. Heck, R. Ellis, P. Dhami, U. D. Kadolsky, M. Kleeman, Y. Kamra, D. J. Fear, S. John, , J. Spencer

The paper identifies an IgMhi developmental trajectory in human B cell maturation that connects T2 progenitors to marginal zone B cells and links its disruption to severe SLE.

bioRxiv · Sep 24, 2020Cell Biology