M. Landreh

This study investigates how cleavage of ZP2 in the egg zona pellucida leads to oligomerization and structural changes that block polyspermy.

This paper demonstrates genomic integration of stop codon suppression systems in mammalian cells to enable homogeneous incorporation of noncanonical amino acids for dual fluorophore labeling.

The paper investigates how NPM1 self-assembly and chaperone activity interact, finding that oligomerization modulates its ability to prevent amyloid formation.

The paper uses mass spectrometry and simulations to study phase separation of RNA-binding proteins, revealing distinct assembly mechanisms and droplet structures.

This study shows that native mass spectrometry can reveal structural features not detectable by AlphaFold2, improving the accuracy of protein structure models.

This study shows that fusing disordered proteins to an engineered spider silk domain improves their translation efficiency and activity in cells.