Author

M. Miihkinen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:microscopy & imaging analysis· 2 Research Focus:development & morphogenesis· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

G. Jacquemet· 5 shared J. Ivaska· 5 shared B. T. Goult· 2 shared R. Saup· 2 shared A. Isomursu· 1 shared A. Popovic· 1 shared A. Stubb· 1 shared C. Guzman· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersCell Biology

G. Jacquemet

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Myosin-X recruits lamellipodin to filopodia tips

M. Miihkinen, A. Popovic, S. Ghimire, R. Saup, M. Grönloh, N. Ball, B. T. Goult, J. Ivaska, G. Jacquemet

The paper identifies lamellipodin as a novel cargo of myosin-X and shows it is transported to filopodia tips to support their formation and stability.

bioRxiv · Aug 17, 2022 · PreprintCell Biology

Conformational dynamics regulate SHANK3 actin and Rap1 binding

S. I. Salomaa, M. Miihkinen, E. Kremneva, I. Paatero, J. Lilja, G. Jacquemet, J. Vuorio, L. Antenucci, F. Hassani-Nia, P. Hollos, A. Isomursu, I. Vattulainen, E. T. Coffey, H.-J. Kreienkamp, P. Lappalainen, J. Ivaska

This study shows SHANK3 binds actin and Rap1 through its SPN domain, with conformational changes regulating this interaction and affecting cellular processes like filopodia formation and autism-related phenotypes.

bioRxiv · Nov 12, 2020 · PreprintCell Biology

Myosin-X and talin modulate integrin activity at filopodia tips

M. Miihkinen, M. L. B. Grönloh, H. Vihinen, E. Jokitalo, B. T. Goult, J. Ivaska, G. Jacquemet

The paper identifies MYO10 and talin as key regulators of integrin activity in filopodia, proposing a two-step model for integrin activation.

bioRxiv · May 5, 2020Cell Biology

Superresolution architecture of pluripotency guarding adhesions

A. Stubb, C. Guzman, E. Närvä, J. Aaron, T.-L. Chew, M. Saari, M. Miihkinen, G. Jacquemet, J. Ivaska

The paper investigates the three-dimensional architecture of unique focal adhesions in human pluripotent stem cells and identifies structural features linked to pluripotency maintenance.

bioRxiv · Sep 19, 2018 · PreprintCell Biology

Filopodome mapping identifies p130Cas as a mechanosensitive regulator of filopodia stability

G. Jacquemet, R. Saup, H. Hamidi, M. Miihkinen, J. Ivaska

The paper maps filopodia adhesions using structured illumination microscopy and identifies p130Cas as a mechanosensitive regulator of filopodia stability.

bioRxiv · Jul 26, 2018Cell Biology