E. Jokitalo

This study shows how herpesvirus infection alters mitochondrial structure and metabolism during infection progression.

This study shows that peroxisomal tail-anchored proteins do not enter the ER but may use mitochondria as an intermediate for their targeting to peroxisomes.

This study shows that IRE1 regulates collagen secretion via P4HB, contributing to liver fibrosis in models of CCl4 and high fat diet.

This study shows that Lgr5+ stem cells in the small intestine adjust their Golgi apparatus orientation to enhance niche signal reception and tissue regeneration, which is impaired with age.

The paper identifies age-related protein structural changes in yeast and shows that inhibiting polymerization of glutamate synthase extends lifespan.

This study shows seipin traps triacylglycerols in the ER membrane via its luminal hydrophobic helices, facilitating their nanoscale clustering and promoting TAG transfer to lipid droplets.

DeepMIB is a user-friendly, open-source tool for training deep learning networks to segment 2D and 3D biological images from light and electron microscopy.

The paper identifies MYO10 and talin as key regulators of integrin activity in filopodia, proposing a two-step model for integrin activation.

The paper develops computational tools for serial block electron microscopy to analyze plasmodesmata distribution and wall environment in Arabidopsis thaliana roots.

This study identifies specialized early peripheral acidic vesicles (eMIIC) in B cells that facilitate rapid antigen processing and MHCII peptide loading for immune response.

This paper introduces a method using fluorescent nanodiamonds for 3D correlative light and electron microscopy to align multi-modal cell imaging data.