Autophagy protects against high-dose Mycobacterium tuberculosis infection
S. Feng, E. M. Nehls, R. L. Kinsella…·C. L. Stallings
This study shows autophagy in myeloid cells protects against high-dose Mycobacterium tuberculosis infection by limiting myeloid-derived suppressor cells and promoting T cell responses, distinct from its role in low-dose infection.