M. Ohlin

Protective non-neutralizing mAbs Ab94 and Ab81 retain high-affinity and potent Fc-mediated function against SARS-CoV-2 variants from Omicron to XBB1.5

IGHV allele similarity clustering improves genotype inference from adaptive immune receptor repertoire sequencing data

The paper introduces a new V allele naming scheme and genotype inference method for adaptive immune receptor sequencing, validated with genomic long read data and implemented in an R package.

A BALB/c IGHV Reference Set, defined by haplotype analysis of long-read VDJ-C sequences from F1 (BALB/c / C57BL/6) mice

The paper defines a BALB/c IGHV reference set by analyzing long-read VDJ-C sequences from F1 mice, identifying strain-specific variations and germline alleles not present in existing genome references.

Opsonization by non-neutralizing antibodies can confer protection to SARS-CoV-2 despite Spike-dependent modulation of phagocytosis

This study shows that non-neutralizing Spike-specific antibodies can enhance phagocytosis of SARS-CoV-2 by monocytes, potentially offering protection despite not neutralizing the virus.

Computational inference, validation, and analysis of 5'UTR-leader sequences of alleles of immunoglobulin heavy chain variable genes

The paper infers and validates 5'UTR-leader sequences of immunoglobulin heavy chain variable gene alleles using transcriptome data and identifies novel upstream regions and variants.

Poorly expressed alleles of several human immunoglobulin heavy chain variable (IGHV) genes are common in the human population

The paper identifies poorly expressed alleles of several human IGHV genes that may be non-functional, challenging previous assumptions about gene deletion in haplotypes.