Author

M. Patrick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1

Frequent Co-Authors

R. T. Annamalai· 3 shared A. B. Aurora· 1 shared A. Bagrodia· 1 shared A. Leach· 1 shared A. M. Poole· 1 shared B. Brooks· 1 shared C. R. Malloy· 1 shared D. Bezwada· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersBioengineering

R. T. Annamalai

Author profile →

4 papers

Recent·Most cited

Maladaptive immune-fibrotic axis drives impaired long bone regeneration under mechanical instability

M. Patrick, J. Ahn, K. D. Hankenson, R. T. Annamalai

This study shows that mechanical instability causes fibrosis and immune dysregulation, impairing bone healing in fractures.

bioRxiv · Oct 26, 2023 · PreprintBioengineering

Mitochondrial metabolism in primary and metastatic human kidney cancers

D. Bezwada, R. J. DeBerardinis, N. P. Lesner, B. Brooks, H. S. Vu, Z. Wu, L. Cai, S. Kasitinon, S. Kelekar, F. Cai, A. B. Aurora, M. Patrick, A. Leach, R. Ghandour, Y. Zhang, , V. Margulis

This study investigates mitochondrial metabolism in kidney cancers, finding that primary tumors have suppressed mitochondrial function while metastases show enhanced TCA cycle labeling.

bioRxiv · Feb 6, 2023Cancer Biology

Licensing Microgels Prolong the Immunomodulatory Phenotype of Mesenchymal Stromal Cells

M. Patrick, R. T. Annamalai

This paper develops microgels that sustain the immunomodulatory phenotype of mesenchymal stromal cells (MSC) by sequestering and releasing IFNγ, enhancing their therapeutic potential in inflammatory conditions.

bioRxiv · Jul 5, 2022 · PreprintBioengineering

Injectable Nanoporous Microgels Generate Vascularized Constructs and Support Bone Regeneration in Critical-sized Defects

M. Patrick, J. Keys, H. Suresh Kumar, R. T. Annamalai

This paper develops injectable microgels that promote bone regeneration and vascularization in critical-sized defects by combining osteogenic and vasculogenic properties.

bioRxiv · Nov 5, 2021Bioengineering