Author

A. B. Aurora

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Leach· 2 shared D. Bezwada· 2 shared R. J. DeBerardinis· 2 shared A. Bagrodia· 1 shared A. M. Poole· 1 shared A. Tasdogan· 1 shared B. Brooks· 1 shared C. R. Malloy· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

A. Leach

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mitochondrial metabolism in primary and metastatic human kidney cancers

D. Bezwada, R. J. DeBerardinis, N. P. Lesner, B. Brooks, H. S. Vu, Z. Wu, L. Cai, S. Kasitinon, S. Kelekar, F. Cai, A. B. Aurora, M. Patrick, A. Leach, R. Ghandour, Y. Zhang, , V. Margulis

This study investigates mitochondrial metabolism in kidney cancers, finding that primary tumors have suppressed mitochondrial function while metastases show enhanced TCA cycle labeling.

bioRxiv · Feb 6, 2023Cancer Biology

G6PD deficiency sensitizes metastasizing melanoma cells to oxidative stress and glutaminolysis

A. B. Aurora, V. Khivansara, A. Leach, J. G. Gill, M. Martin-Sandoval, C. Yang, S. Y. Kastininon, D. Bezwada, A. Tasdogan, W. Gu, T. P. Mathews, Z. Zhao, R. J. DeBerardinis, S. J. Morrison

This study shows that G6PD deficiency in melanoma cells increases oxidative stress and glutaminolysis, reducing metastasis by making cells more vulnerable to metabolic disruption.

bioRxiv · Nov 11, 2021 · PreprintCancer Biology