Author

M. Peeples

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:chicken / avian· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Amer· 1 shared A. Badr· 1 shared A. Eddy· 1 shared A. Forero· 1 shared A. Kenney· 1 shared A. Tedeschi· 1 shared A. Webb· 1 shared A. Zani· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

A. Amer

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2 papers

Recent·Most cited

Caspase-4/11 exacerbates disease severity in SARS-CoV-2 infection by promoting inflammation and thrombosis

M. Eltobgy, A. Zani, A. Kenney, S. Estfanous, E. Kim, A. Badr, C. Carafice, K. Daily, O. Whitham, M. Pietrzak, A. Webb, J. Kawahara, A. Eddy, P. Denz, M. Lu, , A. Amer

This study shows that caspase-4/11 worsens SARS-CoV-2 infection by increasing inflammation and thrombosis, independent of GSDMD, suggesting it as a potential drug target for severe COVID-19.

bioRxiv · Sep 24, 2021Immunology

Mathematical Modeling Identifies the Role of Adaptive Immunity as a Key Controller of Respiratory Syncytial Virus (RSV) Titer in Cotton Rats

D. Wethington, O. Harder, K. Uppulury, W. Stewart, P. Chen, T. King, S. Reynolds, M. Peeples, S. Niewiesk, J. Das

The paper uses mathematical modeling to show that adaptive immunity significantly reduces RSV titer in cotton rats, with key kinetic features observed in both in vitro and in vivo experiments.

bioRxiv · Oct 24, 2018 · PreprintMicrobiology