Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis
A. D. Kenney, S. L. Aron, C. Gilbert, N. Kumar, P. Chen, A. Eddy, L. Zhang, A. Zani, N. Vargas-Maldonado, S. Speaks, J. Kawahara, P. J. Denz, L. Dorn, F. Accornero, J. Ma, , J. S. Yount
This study shows that influenza virus directly infects cardiomyocytes, causing heart dysfunction and fibrosis, challenging the prevailing model of indirect cardiotoxicity.
bioRxiv · Oct 27, 2021Immunology