Author

E. Cho

Cognition Therapeutics (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Biophysics· 1 Cell Biology· 1 Neuroscience· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2

Frequent Co-Authors

A. Hachani· 1 shared A. M. Turner· 1 shared A. Mey· 1 shared A. Pandini· 1 shared A. Ramanathan· 1 shared Allan I. LeveyiD· 1 shared Anthony O. CaggianoiD· 1 shared B. E. E. Turk· 1 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

A. Hachani

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

An interim exploratory biomarker analysis of a Phase 2 clinical trial to assess the impact of CT1812 in Alzheimers disease

Britney N. Lizama, H.A. North, K. Pandey, C. Williams, Duc M. Duong, E. Cho, V. Di Caro, L. Ping, Kaj Blennow, Henrik Zetterberg, James J. Lah, Allan I. Levey, Michael Grundman, Anthony O. Caggiano, Nicholas T. Seyfried, Madison Hamby

This paper reports exploratory CSF proteomics data from a Phase 2 trial of CT1812 in Alzheimer's disease, identifying pharmacodynamic biomarkers and mechanistic insights.

Neurobiology of Disease · Jun 22, 2024Peer-reviewedNeuroscience

Habitat use of loggerhead (Caretta caretta) and green (Chelonia mydas) turtles in the Northwest Pacific Ocean, the northern limit of their distribution range

I.-H. Kim, I.-K. Park, D. Park, M.-S. Kim, I.-Y. Cho, D. Yang, D.-J. Han, E. Cho, W. J. Shim, S. H. Hong, Y.-R. An

This study tracks loggerhead and green turtles in the Northwest Pacific to identify foraging areas and highlights seasonal use of the East Sea despite lower temperatures.

bioRxiv · Aug 6, 2023Zoology

The distinct roles of MSH2 and MLH1 in basal-like breast cancer and immune modulation

T. I. Tithi, J. Mo, N. Borcherding, S. Jo, E. Cho, K. E. Cash, M. Honda, L. Wang, K. K. Ahmed, K. Shirlekar, L. Chen, R. Weigel, H. Kates, K. Gibson-Corley, M. Spies, , W. Zhang

This study identifies distinct roles of MSH2 and MLH1 in basal-like breast cancer, showing MSH2 promotes metastasis while MLH1 enhances it, and reveals MSH2's role in immune modulation through IFNAR1 regulation.

bioRxiv · Jul 20, 2023 · PreprintCancer Biology

Genetic and transcriptomic analysis of hyphal constriction based on a novel assay method in the rice blast fungus

E. Cho, S. H. Lee, M. Jeong, S. Mandal, S.-Y. Park, S. W. Nam, D. G. Byeun, J. K. Choi, Y.-H. Lee, J.-H. Shin, J. Jeon

The paper introduces an in vitro assay to study hyphal constriction in Magnaporthe oryzae, identifying transcriptional changes and a potential histone modification role in this process.

bioRxiv · Jun 14, 2023 · PreprintMicrobiology

The two-component regulator WalKR provides an essential link between cell wall homeostasis with DNA replication in Staphylococcus aureus

L. K. R. Sharkey, R. Guerillot, C. J. Walsh, A. M. Turner, J. Y. H. Lee, S. L. Neville, S. Klatt, S. L. Baines, S. J. Pidot, F. J. Rossello, T. Seeman, H. McWilliam, E. Cho, G. P. Carter, B. P. Howden, , I. R. Monk

This study identifies the WalKR two-component system in Staphylococcus aureus as a polyfunctional regulator linking cell wall homeostasis with DNA replication and other essential processes.

bioRxiv · Feb 27, 2023 · PreprintMicrobiology

Peroxiredoxin 5 regulates osteogenic differentiation via interaction with hnRNPK during bone regeneration

E. Cho, X. Che, M. J. Ang, S. Cheon, J. Lee, K. Kim, C. H. Lee, S.-Y. Lee, H.-Y. Yang, C. Moon, C. Park, J.-Y. Choi, T.-H. Lee

This study identifies Prdx5's role in bone regeneration by regulating osteoblast differentiation through interaction with hnRNPK, impacting osteocalcin expression and osteoclast activity.

bioRxiv · Jun 9, 2022Cell Biology

Structural dynamics of the β-coronavirus Mpro protease ligand binding sites

E. Cho, M. Rosa, R. Anjum, S. Mehmood, M. Soban, M. Mujtaba, K. Bux, S. C. Dantu, A. Pandini, J. Yin, H. Ma, A. Ramanathan, B. Islam, A. Mey, D. BHOWMIK, S. Haider

The paper compares ligand-binding sites of Mpro proteases from SARS-CoV2, SARS-CoV, and MERS-CoV using deep learning and Markov state models to assess structural dynamics and conservation.

bioRxiv · Mar 31, 2021 · PreprintBiophysics

PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK

E. Cho, H. J. Lou, L. Kuruvilla, D. A. Calderwood, B. E. E. Turk

This study identifies PPP6C as a MEK phosphatase that negatively regulates ERK signaling by dephosphorylation, with implications for melanoma therapy resistance.

bioRxiv · Sep 18, 2020Cancer Biology