Cancer BiologybioRxiv
Inhibiting DDX3X triggers tumor-intrinsic type I interferon response and enhances anti-tumor immunity
H. Choi, J. Kwon, J. Sun…·C. Han
This study shows that inhibiting DDX3X in breast cancer cells increases type I interferon response and enhances anti-tumor immunity by promoting antigen presentation and T cell infiltration.
DOI 10.1158/0008-5472.can-20-3790