Author

M. Ceccarelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 7 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Approach:benchmark study· 2 Research Focus:benchmarking· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

D. Bedognetti· 3 shared A. Iavarone· 2 shared J. Galon· 2 shared J. Roelands· 2 shared M. Saad· 2 shared R. Mall· 2 shared W. Hendrickx· 2 shared A. Anichini· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCancer Biology

D. Bedognetti

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Graph-based modeling of multiparametric MRI deciphers molecular states of high-grade glioma invasion with prognostic implications

M. J. Flick, M. Kenaston, S. Sarkar, G. M. LaFond, I. Hart, G. Mazza, J. Cramer, B. R. Bendok, A. Turkmani, C. Krishna, R. Zimmerman, J. Parker, J. Li, K. Donev, K. Bhat, , L. S. Hu

This paper uses graph-based modeling of multiparametric MRI to identify molecular states in high-grade glioma and shows their prognostic significance.

bioRxiv · Jul 8, 2026 · PreprintCancer Biology

A Community Challenge to Predict Clinical Outcomes After Immune Checkpoint Blockade in Non-Small Cell Lung Cancer

M. Mason, O. Lapuente-Santana, A. S. Halkola, W. Wang, R. Mall, X. Xiao, J. Kaufman, J. Fu, J. Pfeil, J. Banerjee, V. Chung, H. Chang, S. D. Chasalow, H. Y. Lin, R. Chai, , B. G. Vincent

The paper evaluates predictive models for immune checkpoint inhibitor outcomes in NSCLC using clinical trial data from two RCTs, finding that models combining PD-L1, TMB, and immune signatures outperform single biomarkers.

Journal of Translational Medicine · Feb 21, 2024Peer-reviewedCancer Biology

Evolutionary adaptation from hydrolytic to oxygenolytic catalysis

S. Bui, S. Gil-Guerrero, P. van der Linden, P. Carpentier, M. Ceccarelli, P. G. Jambrina, R. A. Steiner

This paper investigates how the ABH-fold protein evolved to catalyze oxygenation reactions by repurposing its original hydrolytic function through structural and computational analysis.

bioRxiv · May 5, 2023 · PreprintBiochemistry

Decomprolute: A benchmarking platform designed for multiomics-based tumor deconvolution

S. Feng, A. P. Calinawan, P. Pugliese, P. Wang, M. Ceccarelli, F. Petralia, S. J. Gosline

Decomprolute benchmarks multi-omic tumor deconvolution algorithms using proteogenomic data from CPTAC to improve reproducibility and reusability.

bioRxiv · Jan 5, 2023Cancer Biology

Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy

A. Anichini, A. Molla, G. Nicolini, V. E. Perotti, F. Sgambelluri, A. Covre, C. Fazio, M. F. Lofiego, A. M. Di Giacomo, S. Coral, A. Manca, M. C. Sini, M. Pisano, T. Noviello, F. Caruso, , R. Mortarini

This paper identifies immune-related gene signatures induced by four epigenetic inhibitors in melanoma cells, finding that guadecitabine most strongly upregulates immune-related genes and activates innate immunity pathways.

bioRxiv · Apr 13, 2022Immunology

Germline genetic contribution to the immune landscape of cancer

R. W. Sayaman, M. Saad, V. Thorsson, W. Hendrickx, J. Roelands, Y. Mokrab, F. Farshidfar, T. Kirchhoff, R. F. Sweis, O. F. Bathe, E. Porta-Pardo, M. J. Campbell, C. Stretch, D. Hu, S. Huntsman, , D. Bedognetti

This study identifies germline genetic variants associated with immune traits in cancer, revealing their impact on the tumor immune microenvironment.

bioRxiv · Jan 30, 2020Immunology

Genomic landscape of tumor-host interactions with differential prognostic and predictive connotations

J. Roelands, W. Hendrickx, P. J. K. Kuppen, R. Mall, G. Zoppoli, M. Saad, K. Halliwill, G. Curigliano, D. Rinchai, J. Decock, L. Delogu, T. Turan, J. Samayoa, L. Chouchane, E. Wang, , D. Bedognetti

The paper analyzes tumor-host interactions across 31 cancer types using the ICR signature to identify prognostic and predictive implications of immune phenotypes.

bioRxiv · May 8, 2019Cancer Biology

Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma

J. Yuan, H. M. Levitin, V. Frattini, E. C. Bush, D. M. Boyett, J. Samanamud, M. Ceccarelli, A. Dovas, G. Zanazzi, P. Canoll, J. N. Bruce, A. Lasorella, A. Iavarone, P. A. Sims

This study uses single-cell RNA-Seq to analyze lineage diversity and microenvironment in high-grade gliomas, finding links between cellular identity, proliferation, and population structure.

bioRxiv · Jun 23, 2018Cancer Biology