Multivalent DNA-encoded lectins on phage enable detecting compositional glycocalyx differences
G. M. Lima, Z. J. Chenarboo, M. Sojitra, S. Sarkar, E. J. Carpenter, C. Y.-L. Yang, E. Schmidt, J. Lai, A. Atrazhev, D. Yazdan, C. Peng, E. A. Volker, R. Ho, G. Monteiro, R. Lai, , R. Derda
This paper develops a phage-based liquid lectin array to detect subtle glycocalyx differences by displaying multivalent lectins on DNA-barcoded M13 phage.
bioRxiv · Dec 13, 2023 · PreprintBiochemistry