R. Reddy

Quantification of NAD+ T1 and T2 relaxation times using downfield 1H MRS at 7 T in human brain in vivo

This study measures NAD+ T1 and T2 relaxation times in human brain using 7 T 1H MRS and quantifies the uncertainty propagation in NAD+ concentration.

Ketone supplementation dampens subjective and objective responses to alcohol in rats and humans

This study shows that ketone supplements reduce alcohol's effects in both humans and rats by lowering blood alcohol levels and altering subjective responses.

Graph neural networks ameliorate potential impacts of imprecise large-scale autonomous immunofluorescence labeling of immune cells on whole slide images

This study uses graph neural networks to improve TIL classification on whole slide images by leveraging contextual features from immunofluorescence labeling.

Spatial MIST Technology for Rapid, Highly Multiplexed Detection of Protein Distribution on Brain Tissue

The paper introduces a rapid, highly multiplexed protein detection method for brain tissue, enabling simultaneous detection of 31 proteins in 2 hours with high sensitivity and resolution.

Single-Cell Proteomics Study of Immune Cell Diversity by Quantitating 465 Proteins

This paper introduces a high-multiplex single-cell proteomics technology called Cyclic MIST to measure 465 proteins, enabling comprehensive immune cell subpopulation classification.

Mitochondria-containing EVs Protect Brain Endothelial Cells and Reduce Mouse Brain Infarct Sizes

This paper shows that medium-to-large extracellular vesicles (m/lEVs) protect brain endothelial cells by transferring mitochondria and reducing brain infarct sizes in a mouse stroke model.

MXtrodes: MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation

This paper introduces MXtrodes, a new class of bioelectronic interfaces using MXene for high-resolution, large-scale electrophysiology and stimulation, validated in human and animal applications.

Post-transcriptional regulation of redox homeostasis by the small RNA SHOxi in haloarchaea

This study identifies SHOxi, an sRNA in Haloferax volcanii, which regulates redox homeostasis by destabilizing malic enzyme mRNA during oxidative stress.

Genetically Encoded, Multivalent Liquid Glycan Array (LiGA)

The paper introduces LiGA, a platform for analyzing glycan-lectin interactions using DNA barcoded phage displaying glycans, enabling in vitro and in vivo binding studies.

Regulatory non-coding small RNAs are diverse and abundant in an extremophilic microbial community

The paper identifies diverse and abundant regulatory small RNAs in an extremophilic microbial community using metatranscriptomic analysis and a new sRNA annotation pipeline.