Author

M. T. Myers

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Ke· 1 shared C. Hu· 1 shared M. L. Lozen· 1 shared X. Zhou· 1 shared Y. Zhang· 1 shared Z. Hou· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

A. Ke

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1 paper

Recent·Most cited

BiochemistrybioRxivAug 5, 2023

Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications

C. Hu, M. T. Myers, X. Zhou…·A. Ke

This study defines the DNA binding and cleavage mechanisms of Type I-C CRISPR-Cas3 using cryo-EM and identifies anti-CRISPR proteins that inhibit its activity in human cells.

DOI 10.1016/j.molcel.2023.12.034

humanstructural biology

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