Author

M. Uzzan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Assay:clinical cohort / trial· 1 Organism:mouse· 1

Frequent Co-Authors

M. Tokuyama· 3 shared S. Mehandru· 3 shared A. Cerutti· 2 shared A. D. Polydorides· 2 shared A. Krek· 2 shared A. Livanos· 2 shared A. Seki· 2 shared B. K. Chen· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

M. Tokuyama

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Author profile →

3 papers

Recent·Most cited

HIV-1 infection is associated with depletion of germinal center B cells and a decrease in IgA+ plasma cells in the GI tract

F. Cossarini, J. Shang, A. Krek, Z. Al-taie, R. Hou, P. Canales-Herrerias, M. Tokuyama, M. Tankelevich, A. Tillowiz, D. Jha, A. Livanos, L. Leyre, M. Uzzan, G. Martinez-Delgado, M. D. Taylor, , S. Mehandru

bioRxiv · May 17, 2024Immunology

Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis

P. Canales-Herrerias, M. Uzzan, A. Seki, R. S. Czepielewski, B. Verstockt, A. Livanos, F. Raso, A. Dunn, D. Dai, A. Wang, Z. Al-taie, J. Martin, H. M. Ko, M. Tokuyama, M. Tankelevich, , S. Mehandru

This study investigates the mechanism of vedolizumab in ulcerative colitis by analyzing immune cell changes in gut-associated lymphoid tissue and shows that targeting GALT is a novel mechanism of action.

bioRxiv · Jan 19, 2023Immunology

Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1 infected individuals

M. Uzzan, M. Tokuyama, A. K. Rosenstein, C. Tomescu, I. N. SahBandar, H. M. Ko, L. Leyre, A. Chokola, E. Kaplan-Lewis, G. Rodriguez, A. Seki, M. J. Corley, J. Aberg, A. La Porte, E.-y. Park, , S. Mehandru

Anti-α4β7 therapy reduces lymphoid aggregates in the gastrointestinal tract of HIV-1 infected individuals with mild inflammatory bowel disease.

bioRxiv · Jun 14, 2018Immunology