Threonine phosphorylation regulates the molecular assembly and signaling of EGFR in cooperation with membrane lipids
R. Maeda, H. Tamagaki-Asahina, T. Sato…·Y. Sako
This study shows that threonine phosphorylation in EGFR's JM domain switches its function from kinase activation dimers to scaffolding oligomers, influenced by membrane lipids.