N. Gagnon

This study uses single-cell multi-omics profiling to show arsenic alters macrophage transcription and epigenetics in atherosclerotic plaques, with more profound epigenetic changes.

This study uses PhenoCycler imaging to analyze the tumor microenvironment in murine cancer models, revealing distinct TME features and cell-cell contact differences across cancer types.

This study evaluates the impact of peri-weaning feeding strategies on gut microbial diversity and activity in piglets, finding limited effects on weight gain but modulatory effects on the microbiota.

This paper identifies a metabolic vulnerability in melanoma cells by disrupting peroxisomes and shows that combining this with MAPK-targeted therapies enhances anti-tumor effects.

This study identifies the MNK1/2-eIF4E axis as a driver of melanoma phenotype switching, progression, and immunotherapy resistance, with potential therapeutic targeting.