Cell BiologybioRxivPreprint
Upregulated PD-1 Signaling is an Important Antagonist to Glomerular Health in Aged Kidneys
J. W. Pippin, N. Kaverina, Y. Wang…·S. J. Shankland
This study shows that upregulated PD-1 signaling in aged kidneys impairs podocyte health and that anti-PD-1 treatment improves podocyte aging and kidney function.
DOI 10.1101/2021.10.26.466006