A Novel Role of Hyaluronan and its Membrane Receptors, CD44 and RHAMM in Obesity-Related Glomerulopathy
B. Qi, V. Musale, X. Weng, A. K. Banah, C. Murdoch, A. C. Lay, K. J. Heesom, W. Ju, M. Bitzer, C. Hills, R. J. Coward, L. Kang
This study identifies HA and its receptors CD44/RHAMM as key drivers of obesity-related glomerulopathy, showing their role in renal inflammation, fibrosis, and dysfunction, and suggests they as therapeutic targets.
bioRxiv · Jun 22, 2024 · PreprintPhysiology