Author

N. Kubo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Ren· 2 shared R. Hu· 2 shared B. Li· 1 shared G. P. McVicker· 1 shared H. Ohishi· 1 shared H. Sasaki· 1 shared K. Shirane· 1 shared K. Zhang· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

B. Ren

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Combined and differential roles of ADD domains of DNMT3A and DNMT3L on DNA methylation landscapes in mouse germ cells

N. Kubo, R. Uehara, S. Uemura, H. Ohishi, K. Shirane, H. Sasaki

This study examines the roles of ADD domains in DNMT3A and DNMT3L in DNA methylation in mouse germ cells, finding that their combined loss leads to severe methylation defects.

bioRxiv · Sep 7, 2023Cell Biology

MLL3/MLL4 Histone Methyltranferase Activity Dependent Chromatin Organization at Enhancers during Embryonic Stem Cell Differentiation

N. Kubo, R. Hu, Z. Ye, B. Ren

This study investigates how MLL3/MLL4 histone methyltransferase activity influences enhancer-promoter contacts and gene activation during mouse embryonic stem cell differentiation.

bioRxiv · Mar 17, 2021 · PreprintCell Biology

Discovery and Functional Characterization of Pro-growth Enhancers in Human Cancer Cells

P. Chen, P. Fiaux, B. Li, K. Zhang, N. Kubo, S. Jiang, R. Hu, S. Wu, M. Wang, W. Wang, G. P. McVicker, P. Mischel, B. Ren

The paper identifies and characterizes pro-growth enhancers in cancer cells using CRISPR screens, finding lineage-specific enhancers associated with poor prognosis and potential therapeutic targets.

bioRxiv · Feb 4, 2021 · PreprintCancer Biology