Author

M. Ejemel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Y. Wang· 5 shared L. A. Cavacini· 3 shared Q. Li· 3 shared Z. A. Schiller· 3 shared A. Amcheslavsky· 2 shared J. R. Toomey· 2 shared M. S. Klempner· 2 shared M. Stoppato· 2 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

Y. Wang

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structural Elucidation of a Protective B cell Epitope on Outer Surface Protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi

M. J. Rudolph, S. Davis, H. M. E. Haque, D. D. Weis, D. J. Vance, C. L. Piazza, M. Ejemel, L. A. Cavacini, Y. Wang, L. Mbow, R. D. Gilmore, N. J. Mantis

This paper determines the crystal structure of a protective B cell epitope on OspC, revealing its quaternary nature and informing vaccine design for Lyme disease.

bioRxiv · Nov 28, 2022 · PreprintImmunology

Conformational dynamics and allosteric modulation of the SARS-CoV-2 spike

M. A. Diaz-Salinas, Q. Li, M. Ejemel, L. Yurkovetskiy, J. Luban, K. Shen, Y. Wang, J. B. Munro

This study investigates how ACE2 and antibodies affect the conformational dynamics of the SARS-CoV-2 spike protein using smFRET and FCS, revealing that D614G modulates RBD energetics similar to ACE2 binding.

bioRxiv · Oct 29, 2021Biophysics

Oral administration of a single anti-CfaE nanobody provides broadly cross-protective immunity against major pathogenic Enterotoxigenic Escherichia coli strains

A. Amcheslavsky, A. Wallace, M. Ejemel, Q. Li, C. McMahon, M. Stoppato, S. Giuntini, Z. A. Schiller, J. Pondish, J. R. Toomey, R. Schneider, J. Meisinger, R. Heukers, A. C. Kruse, E. M. Barry, , Y. Wang

This study shows that oral administration of a single nanobody provides broad protection against multiple ETEC strains by targeting conserved epitopes.

bioRxiv · Jun 16, 2020 · PreprintMicrobiology

IgA MAb blocks SARS-CoV-2 Spike-ACE2 interaction providing mucosal immunity

M. Ejemel, Q. Li, S. Hou, Z. A. Schiller, A. L. Wallace, A. Amcheslavsky, N. Kurt Yilmaz, J. R. Toomey, R. Schneider, B. J. Close, D.-Y. Chen, H. L. Conway, M. Saeed, L. A. Cavacini, M. S. Klempner, , Y. Wang

This study identifies an IgA monoclonal antibody that blocks SARS-CoV-2 Spike-ACE2 interaction and provides mucosal immunity.

bioRxiv · May 15, 2020 · PreprintMicrobiology

Identification and Characterization of Human Monoclonal Antibodies for Immunoprophylaxis Against Enterotoxigenic Escherichia coli Infection

S. Giuntini, M. Stoppato, M. Sedic, M. Ejemel, J. R. Pondish, D. Wisheart, Z. A. Schiller, W. D. Thomas, E. Barry, L. Cavacini, M. Klempner, Y. Wang

This study identifies human monoclonal antibodies against CfaE that inhibit ETEC colonization and reduce intestinal colonization in mice.

bioRxiv · May 11, 2018Microbiology