N. Mitra

Mutational analysis of the F plasmid partitioning protein ParA reveals novel residues required for oligomerisation and plasmid maintenance

This study identifies mutations in ParA that disrupt polymerization and plasmid maintenance, highlighting the role of ParA oligomerization in plasmid partitioning.

A cobB like protein in Oryza sativa indica regulates the mitochondrial machinery under stress conditions

This paper identifies a new class III sirtuin in Oryza sativa indica that regulates mitochondrial and nuclear processes under stress conditions.

A salt bridge-mediated resistance mechanism to FtsZ inhibitor PC190723 revealed by a cell-based screen

This paper develops a cell-based assay to screen for FtsZ inhibitors and identifies a salt bridge-mediated resistance mechanism to PC190723 in Helicobacter pylori FtsZ.

Biochemical analysis of deacetylase activity of rice sirtuin OsSRT1, a class IV member in plants

The paper investigates the deacetylase activity of OsSRT1, a plant sirtuin, showing its ability to deacetylate histones and non-histone targets, and its response to abiotic stress.

Understanding the mechanism of monoADP ribosylation in OsSRT1 and its linkage to the DNA repair system under stress conditions

This paper investigates OsSRT1's dual enzymatic activity in plants, showing its preference for mono-ADP ribosylation over deacetylation and its link to DNA repair under stress.

Filament dynamics driven by ATP hydrolysis modulates membrane binding of the bacterial actin MreB

This study shows that ATP hydrolysis modulates MreB filament dynamics and membrane binding, affecting filament length, bundling, and curvature-dependent orientation.

Cohesin depleted cells rebuild functional nuclear compartments after endomitosis

The paper shows cohesin-depleted cells undergo endomitosis and rebuild a multilobulated nucleus with functional compartments despite lacking cohesin.