D. Mishra

Mutational analysis of the F plasmid partitioning protein ParA reveals novel residues required for oligomerisation and plasmid maintenance

This study identifies mutations in ParA that disrupt polymerization and plasmid maintenance, highlighting the role of ParA oligomerization in plasmid partitioning.

Conformational switch of a peptide provides a novel strategy to design peptide loaded porous organic polymer for Pyroptosis pathway mediated cancer therapy

This paper designs a peptide-loaded porous organic polymer that undergoes a conformational switch in cancer cells, triggering pyroptosis via membrane pore formation.

Listeria adhesion protein orchestrates caveolae-mediated apical junctional remodeling of epithelial barrier for L. monocytogenes translocation

This study shows LAP promotes L. monocytogenes translocation by remodeling epithelial junctions via caveolae-mediated endocytosis.

Natural genomic variation in rice blast genomes is associated with specific heterochromatinmodifications

The paper examines DNA sequence variation in rice blast fungi, finding that heterochromatin-associated histone marks correlate with SNP and INDEL frequency, even after accounting for selection.

Extended lifespan in female Drosophila melanogaster through late-life caloric restriction.

This study shows that late-life caloric restriction extends lifespan in female Drosophila melanogaster by reducing mortality and altering reproductive energy allocation.

Late- life shift in caloric intake affects fly longevity and metabolism

This study shows that switching to a low-calorie diet late in life extends fly lifespan and reduces mortality, while switching to a high-calorie diet shortens lifespan and increases mortality.

The distinctive mechanical and structural signatures of residual force enhancement in myofibers

The paper investigates titin's role in residual force enhancement (RFE) in muscle by analyzing structural changes in myofibers with and without titin cleavage and in a mutant strain.

RNA silencing by CRISPR in plants does not require Cas13

The paper shows that CRISPR-Cas13 can reduce RNA in plants without the Cas13 protein, using a mechanism similar to RNAi.

Differential expression of proteins in human prostate cancer tissues probed by MALDI imaging mass spectrometry

The paper uses MALDI imaging mass spectrometry to identify differentially expressed proteins in human prostate cancer tissues and suggests potential diagnostic biomarkers.