Author

N. Nagathihalli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Bianchi· 2 shared A. R. Dosch· 2 shared I. De Castro Silva· 2 shared J. Datta· 2 shared N. Merchant· 2 shared S. Mehra· 2 shared S. Singh· 2 shared V. T. Garrido· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. Bianchi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivMay 1, 2022

Distinct Mechanisms of Innate and Adaptive Immune Regulation Underlie Poor Oncologic Outcomes Associated with KRAS-TP53 Co-Alteration in Pancreatic Cancer

J. Datta, A. Bianchi, I. De Castro Silva…·N. B. Merchant

DOI 10.1038/s41388-022-02368-w

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 7, 2021

Combined MEK and STAT3 inhibition reprograms stromal inflammation to overcome immunotherapy resistance in pancreatic cancer

J. Datta, X. Dai, A. Bianchi…·N. Merchant

This paper shows that combining MEK and STAT3 inhibitors reprograms stromal inflammation and enhances immunotherapy response in pancreatic cancer.

DOI 10.1101/2021.03.07.434236

mousebulk RNA-seq

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Cancer BiologyCell Death & DiseasePeer-reviewedNov 11, 2020

Stroma secreted IL6 selects for stem-like population and alters pancreatic tumor microenvironment by reprogramming metabolic pathways

K. Kesh, V. T. Garrido, A. Doesch…·S. Banerjee

This study shows that stromal IL6 promotes stem-like cells and metabolic reprogramming in pancreatic tumors, creating an immune-evasive microenvironment that can be targeted to improve checkpoint inhibitor therapy.

DOI 10.1038/s41419-020-03168-4

mousebulk RNA-seq

𝕏 PostBluesky