Author

O. Herault

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Robert· 2 shared C. Vandier· 2 shared D. Crottes· 2 shared J. Bourgeais· 2 shared J.-F. Dumas· 2 shared M. Gueguinou· 2 shared T. Lecomte· 2 shared W. Raoul· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

A. Robert

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Encoding of the colorectal cancer metabolic program through MICU2

A. Robert, D. Crottes, J. Bourgeais, N. Gueguen, A. Chevrollier, J.-F. Dumas, S. Servais, I. Domingo, S. Chadet, J. Sobilo, O. Herault, T. Lecomte, C. Vandier, W. Raoul, M. Gueguinou

This study investigates the role of MICU2 in colorectal cancer metabolism, showing its importance in mitochondrial function, metabolic flexibility, and tumor progression.

bioRxiv · Oct 31, 2023 · PreprintCancer Biology

Low concentrations of ethylene bisdithiocarbamate pesticides maneb and mancozeb impair manganese and zinc homeostasis to induce oxidative stress and caspase-dependent apoptosis in human hepatocytes

K. Petitjean, Y. Verres, S. Bristeau, C. Ribault, C. Aninat, C. Olivier, P. Leroyer, M. Ropert, O. Loreal, O. Herault, L. Amalric, N. Baran, B. Fromenty, A. Corlu, P. Loyer

This study shows that low concentrations of maneb and mancozeb, Mn-containing fungicides, disrupt Mn and Zn homeostasis, induce oxidative stress, and cause caspase-dependent apoptosis in human hepatocytes.

bioRxiv · Jul 11, 2023Pharmacology & Toxicology

Curcumin and NCLX Inhibitors Share Anti-Tumoral Mechanisms in Microsatellite-Instability-Driven Colorectal Cancer

M. Gueguinou, S. Ibrahim, J. Bourgeais, A. Robert, T. Pathak, X. Zhang, D. Crottes, J. Dupuy, D. Ternant, V. Monbet, R. Guibon, H. Flores-Romero, A. Lefevre, S. Lerondel, A. Le Pape, , T. Lecomte

This study identifies NCLX as a therapeutic target in MSI-driven CRC, showing that curcumin and NCLX inhibitors induce anti-tumoral effects through mitochondrial calcium overload and apoptosis.

bioRxiv · Jan 18, 2022Cancer Biology