P. Aerts

A Workflow for High Through-Put, High Precision Livestock Diagnostic Screening of Locomotor Kinematics

This paper develops a workflow using deep learning and kinematic analysis to identify developmental delays in piglets through locomotion patterns.

Promoting Fc-Fc interactions between anti-capsular antibodies provides strong complement-dependent immune protection against Streptococcus pneumoniae

This paper shows that modifying anti-capsular antibodies to enhance hexamerization improves complement activation and immune protection against Streptococcus pneumoniae.

C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases

This study shows that C1r2s2 proteases stabilize C1q binding to surface-bound IgG, with subclass-specific effects and improved phagocytosis with hexamer-enhanced IgGs.

The impact of Staphylococcus aureus cell wall glycosylation on langerin recognition and Langerhans cell activation

This study investigates how different glycosylation patterns on Staphylococcus aureus cell walls affect langerin recognition and Langerhans cell activation, finding that β-GlcNAc is sufficient for langerin binding regardless of its position on WTA.

Staphylococcal protein A inhibits complement activation by interfering with IgG hexamer formation

This study shows Staphylococcal protein A inhibits IgG hexamer formation, blocking complement activation, but IgG3 can still induce complement activation despite SpA.