Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production.
B. Bao, Y. Wang, P. Boudreau, X. Song, M. Wu, X. Chen, I. Patik, Y. Tang, J. D. Ouahed, A. Ringel, J. Barends, C. Wu, E. P. Balskus, J. R. Thiagarajah, J. Liu, , S. Snapper
This study shows that bacterial sphingolipids worsen colitis by reducing IL-22 production from ILC3 cells in mice.
bioRxiv · Sep 5, 2023Immunology