Author

B. H. Horwitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Y. Tang· 3 shared B. Bao· 2 shared I. Patik· 2 shared S. Snapper· 2 shared A. Eran· 1 shared A. H. Owings· 1 shared A. K. Shalek· 1 shared A. Nandy· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

Y. Tang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivSep 5, 2023

Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production.

B. Bao, Y. Wang, P. Boudreau…·S. Snapper

This study shows that bacterial sphingolipids worsen colitis by reducing IL-22 production from ILC3 cells in mice.

DOI 10.1053/j.gastro.2023.11.200

mouseproteomics

𝕏 PostBluesky

ImmunologyMucosal ImmunologyPeer-reviewedJun 1, 2023

IL-10 inhibits STAT1-dependent macrophage accumulation during microbiota-induced colitis

I. Patik, N. S. Redhu, A. Eran…·B. H. Horwitz

The paper shows IL-10R inhibits STAT1-dependent macrophage accumulation in colitis by preventing a cell-extrinsic signal, not directly affecting STAT1 function.

DOI 10.1016/j.mucimm.2023.02.006

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivFeb 20, 2021

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

C. G. K. Ziegler, V. N. Miao, A. H. Owings…·J. Ordovas-Montanes

This study analyzes nasopharyngeal samples from COVID-19 patients and healthy controls to identify how SARS-CoV-2 infection affects respiratory epithelial cells and immune responses, finding impaired local intrinsic immunity in severe cases.

DOI 10.1016/j.cell.2021.07.023

𝕏 PostBluesky