P. Bronsert

Proteomic Characterization of Intrahepatic Cholangiocarcinoma Identifies Distinct Subgroups and Proteins Associated with Time-To-Recurrence

This study identifies two proteomic subgroups of intrahepatic cholangiocarcinoma with distinct time-to-recurrence rates and biological processes.

Targeted and Explorative Profiling of Kallikrein Proteases and Global Proteome Biology of Pancreatic Ductal Adenocarcinoma, Chronic Pancreatitis, and Normal Pancreas Highlights Disease-Specific Proteome Remodelling

This study profiles kallikrein proteases and global proteomes in PDAC, CP, and normal pancreas, identifying disease-specific proteomic changes and variants.

Hourglass, a tool to mine bioimaging data, uncovers sex-disparities in the IL-6-associated T cell response in pancreatic tumors

Hourglass processes bioimaging data to reveal sex-specific IL-6 effects on T cell responses in pancreatic tumors.

Proteome biology of primary colorectal carcinoma and corresponding liver metastases

This study compares the proteome of primary colorectal carcinomas and their corresponding liver metastases, identifying distinct proteomic profiles and biological processes.

Adaptive subsets limit the anti-tumoral NK-cell activity in Hepatocellular Carcinoma

This study shows that adaptive NK cells have reduced anti-tumoral activity in HCC patients, particularly in those with HBV infection, and are expanded in such cases.

Spatially confined sub-tumor microenvironments orchestrate pancreatic cancer pathobiology

This study identifies spatially confined sub-tumor microenvironments in PDAC that drive distinct tumor progression outcomes.