M. Werner

Versatile roles of Annexin A4 in ccRCC: impact on membrane repair, transcriptional signatures, and composition of the tumor microenvironment

This study identifies ANXA4 as a key player in ccRCC, showing its role in membrane repair, transcriptional changes, and tumor microenvironment composition through genetic and computational analyses.

Silybin A from Silybum marianum reprograms lipid metabolism to induce a cell fate-dependent class switch from triglycerides to phospholipids

This study identifies silybin A's role in reprogramming lipid metabolism to shift from triglycerides to phospholipids in liver cells, with implications for liver protection.

Proteomic Characterization of Intrahepatic Cholangiocarcinoma Identifies Distinct Subgroups and Proteins Associated with Time-To-Recurrence

This study identifies two proteomic subgroups of intrahepatic cholangiocarcinoma with distinct time-to-recurrence rates and biological processes.

Microwave assisted acidification for green hydrogen and organic acids production

This study compares microwave and oven heat shocks for enhancing green hydrogen and organic acid production in anaerobic digestion, finding microwave treatment offers better repeatability and microbiome shifts.

Halophilic nematodes live in America's Dead Sea

The paper reports the discovery of novel halophilic nematodes in microbialites of the Great Salt Lake, UT, expanding knowledge of halophile ecosystems and habitable limits of animals.

Single molecule MATAC-seq reveals key determinants of DNA replication origin efficiency

The paper develops MATAC-Seq to analyze single-molecule chromatin accessibility at replication origins, identifying chromatin features that predict origin efficiency in yeast.

The CGG triplet repeat binding protein 1 counteracts DNA secondary structure-induced transcription-replication conflicts

This study shows CGGBP1 binds to short trinucleotide repeats to prevent transcription-replication conflicts caused by secondary DNA structures.

Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from cystic fibrosis patients

The paper shows that scorpionfish-derived BPI (scoBPI) is effective against drug-resistant Pseudomonas aeruginosa in CF patients, even when human BPI is neutralized by autoantibodies.

Honey Bees Get Map Coordinates from the Dance

This study shows honeybees use the waggle dance to obtain both a flying direction and a map-like coordinate system to locate food sources.

Preclinical models of human multiple myeloma subgroups

This study generates preclinical models of human multiple myeloma subgroups by inducing specific genetic alterations in mice, showing their resemblance to human disease.

Protein corona modulates interaction of spiky nanoparticles with lipid bilayers

This study shows that protein corona alters how spiky nanoparticles interact with lipid bilayers, suppressing pore formation by reducing spike exposure.