P. Catalan

Nuclear phylogenomics of grasses (Poaceae) supports current classification and reveals repeated reticulation

This study constructs a nuclear phylogeny of grasses using genome-scale data, showing agreement with plastome phylogeny and evidence for repeated reticulation events.

Full factorial construction of synthetic microbial communities

The paper introduces a low-cost method to assemble all possible combinations of microbial strains, demonstrating it with eight Pseudomonas aeruginosa strains to identify optimal consortia.

Frequent emergence of resistance mutations following complex intra-host genomic dynamics in SARS-CoV-2 patients receiving Sotrovimab

This study tracks resistance mutation emergence in SARS-CoV-2 patients treated with Sotrovimab, finding 68% resistance in BA.5 lineage with rapid onset and complex mutation dynamics.

Scattered differentiation of unlinked loci across the genome underlines ecological divergence of the selfing grass Brachypodium stacei

This study identifies scattered genetic divergence across the genome in sympatric Brachypodium stacei populations adapting to contrasting environments with ongoing gene flow.

Discovery and molecular basis of chloride as an allosteric activator and catalytic inhibitor for Class-D beta-lactamases.

The paper identifies chloride as an allosteric activator and inhibitor of Class-D beta-lactamases, revealing its dual role in enzyme kinetics and suggesting new antibiotic strategies.

Day length-dependent thermal COP1 dynamics integrate conflicting seasonal cues in the control of Arabidopsis elongation

The paper develops a mathematical model to understand how COP1 integrates day length and temperature cues to control Arabidopsis hypocotyl elongation, revealing COP1's role in temperature signaling during the day.

Patterns of pan-genome occupancy and gene co-expression under water-deficit in Brachypodium distachyon.

The paper integrates pan-genomic analysis with transcriptomic data to examine how gene occupancy and co-expression patterns differ under drought stress in Brachypodium distachyon.

Tracking the Ancestry of Known and 'Ghost' Homeologous Subgenomes in Model Grass Brachypodium Polyploids

The paper identifies subgenomes in Brachypodium polyploids using phylogenomic methods and confirms the existence of ancestral genomes in polyploids.

Clinical Antibiotic Resistance Patterns Across 70 Countries

The paper analyzes global antibiotic resistance patterns using clinical data from 70 countries, identifying resistance dynamics and proposing a phase plane method to detect resistance risk.

Parsimonious scenario for the emergence of viroid-like replicons de novo

The paper evaluates the plausibility of de novo emergence of viroid-like replicons through a theoretical analysis of RNA structure evolution and functional module acquisition.