Author

P. Cullen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

B. Tiwari· 2 shared J. F. Curtin· 2 shared A. M. deCarvalho· 1 shared A. Prabhakar· 1 shared B. Collins· 1 shared B. Gonzalez· 1 shared B. Simonetti· 1 shared C. McConville· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCancer Biology

B. Tiwari

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Ultrasound-mediated drug diffusion, uptake, and cytotoxicity in glioblastoma 3D tumour sphere model

J. Wanigasekara, J. R. M. Mondala, P. Cullen, B. Tiwari, J. F. Curtin

This study shows ultrasound enhances drug diffusion, uptake, and cytotoxicity in 3D glioblastoma spheroids compared to 2D cultures, improving treatment efficacy.

bioRxiv · Oct 26, 2023Cancer Biology

Structure of the Commander endosomal trafficking complex linked to X-linked intellectual disability/Ritscher-Schinzel syndrome

M. Healy, K. McNally, R. Butkovic, M. Chilton, K. Kato, J. Sacharz, C. McConville, E. Moody, S. Shaw, V. Planelles-Herrero, S. Yadav, J. Ross, U. Borucu, C. Palmer, K.-E. Chen, , P. Cullen

The paper presents the structural model of the Commander endosomal trafficking complex, identifies disease-causing mutations, and reveals its molecular function in trafficking.

bioRxiv · Jan 25, 2023 · PreprintBiochemistry

Pin Electrode Reactor: A novel cold atmospheric plasma device and its potential in glioblastoma treatment

A. M. deCarvalho, S. Behan, L. Scally, C. Sarangapani, R. Malone, P. Cullen, B. Tiwari, J. F. Curtin

This study evaluates a novel pin electrode reactor for cold atmospheric plasma treatment of glioblastoma cells, showing cytotoxicity dependent on dose, time, and reactive oxygen species.

bioRxiv · Jan 8, 2021 · PreprintCancer Biology

Spatiotemporal Control of Pathway Sensors and Cross-Pathway Feedback Regulate a Cell Differentiation MAPK Pathway in Yeast

A. Prabhakar, B. Gonzalez, H. Dionne, S. Basu, P. Cullen

The paper shows that temporal and spatial regulation of pathway sensors and cross-pathway feedback control the fMAPK pathway in yeast.

bioRxiv · Dec 18, 2020Cell Biology

A heterodimeric SNX4:SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly

Z. Anton, V. Betin, B. Simonetti, C. Traer, N. Attar, P. Cullen, J. Lane

This study identifies the SNX4:SNX7 heterodimeric SNX-BAR complex as essential for ATG9A trafficking and autophagosome assembly in mammalian cells.

bioRxiv · Mar 15, 2020Cell Biology