Author

P. Droge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Siddiqui· 1 shared C. Chua· 1 shared C. Verma· 1 shared H. Hentze· 1 shared I. B. Tan· 1 shared J. F. Ghadessy· 1 shared J. Yan· 1 shared L. S. Yi· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A. A. Siddiqui

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2 papers

Recent·Most cited

Expanding the DNA editing toolbox: novel lambda integrase variants targeting microalgal and human genome sequences.

S. J. Wei, A. A. Siddiqui, L. S. Yi, S. Kannan, S. Peter, Z. Yingying, C. Verma, P. Droge, J. F. Ghadessy

This paper describes the directed evolution of lambda integrase variants that target microalgal and human genome sequences, showing enhanced specificity for non-natural sites.

bioRxiv · Sep 22, 2023 · PreprintBioengineering

The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivity

S. M. Ahmed, P. D. Ramani, S. Q. R. Wong, X. Zhao, R. Ivanyi-Nagy, T. C. Leong, C. Chua, Z. Li, H. Hentze, I. B. Tan, J. Yan, R. DasGupta, P. Droge

This paper identifies HMGA2 as a regulator of DNA supercoiling and replication fork stability, showing its protective role against DNA damage from topoisomerase poisons and its potential as a therapeutic marker in cancer.

bioRxiv · Feb 8, 2019Cancer Biology