Structure and mechanism of the human TMEM260 O-mannosyltransferase
Javier O. Cifuente, Lorenzo Povolo, Borja Ochoa-Lizarralde…·Iban Ubarretxena‐Belandia
This study determines the cryo-EM structure of human TMEM260, revealing its mechanism for O-mannosylation of key receptors and providing insights into related congenital disorders.