Author

P. K. Reville

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

L. Wang· 2 shared M. R. Green· 2 shared R. Wang· 2 shared A. Choi· 1 shared A. Futreal· 1 shared B. Liu· 1 shared C. C. Le· 1 shared C. Okwuchi· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

L. Wang

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 28, 2023

CD8 T-cell dysfunction is linked with CAR T-cell failure and can be mitigated by a non-alpha IL-2 agonist, pegenzileukin

P. K. Reville, I. N. Sheikh, A. Choi…·M. R. Green

The paper identifies dysfunctional CD8 CAR T-cells in rrLBCL tumors and shows that pegenzileukin mitigates this dysfunction, improving CAR T-cell responses.

DOI 10.1101/2023.08.28.555127

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivSep 3, 2020

Single-cell Characterization of Acute Myeloid Leukemia and its Microenvironment Following PD-1 Blockade Based Therapy

H. A. Abbas, D. Hao, K. Tomczak…·A. Futreal

This study analyzes single-cell RNA and TCR profiles from AML patients before and after PD-1 blockade therapy to identify factors influencing response and resistance.

DOI 10.1038/s41467-021-26282-z

humanscRNA-seq

𝕏 PostBluesky