Author

P. Pajic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 1

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Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Approach:statistical model· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

O. Gokcumen· 3 shared S. Ruhl· 3 shared A. Globig· 1 shared A. Varki· 1 shared A.-M. Torregrossa· 1 shared B. K. Alford-Lawrence· 1 shared B. R. Wasik· 1 shared C. Karageorgiou· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersEvolutionary Biology

O. Gokcumen

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Author profile →

4 papers

Recent·Most cited

Emergence of saliva protein genes in the secretory calcium-binding phosphoprotein (SCPP) locus and accelerated evolution in primates

P. Pajic, L. Landau, O. Gokcumen, S. Ruhl

This study investigates the evolution of saliva-related SCPP genes, identifying convergent duplications and positive selection in primates, with implications for adaptive diversification of saliva composition.

bioRxiv · Feb 14, 2024 · PreprintEvolutionary Biology

Paleolithic Gene Duplications Primed Adaptive Evolution of Human Amylase Locus Upon Agriculture

F. Yilmaz, C. Karageorgiou, K. Kim, P. Pajic, K. Scheer, Human Genome Structural Variation Consortium, C. R. Beck, A.-M. Torregrossa, C. Lee, O. Gokcumen

The paper resolves the amylase locus at nucleotide resolution in modern and ancient humans, showing AMY1 copy number variation predated agriculture and was driven by recombination.

bioRxiv · Nov 27, 2023Evolutionary Biology

The effects of modified sialic acids on mucus and erythrocytes on influenza A virus HA and NA functions

K. N. Barnard, B. K. Alford-Lawrence, D. W. Buchholz, B. R. Wasik, J. R. LaClair, H. Yu, R. Honce, S. Ruhl, P. Pajic, E. K. Daugherity, X. Chen, S. Schultz-Cherry, H. C. Aguilar, A. Varki, C. R. Parrish

This study examines how modified sialic acids in mucus and erythrocytes affect influenza A virus HA and NA functions, finding that these modifications inhibit viral binding and cleavage.

bioRxiv · Oct 10, 2019 · PreprintMicrobiology

Amylase copy number analysis in several mammalian lineages reveals convergent adaptive bursts shaped by diet

P. Pajic, P. Pavlidis, K. Dean, L. Neznanova, E. Daugherity, R.-A. Romano, D. Garneau, A. Globig, S. Ruhl, O. Gokcumen

The paper analyzes amylase copy number in mammals, finding convergent adaptive expansions linked to starch diets and increased enzymatic activity.

bioRxiv · Jun 5, 2018Evolutionary Biology