Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel
X. Mo, P. Pang, Y. Wang, D. Jiang, M. Zhang, Y. Li, P. Wang, Q. Geng, C. Xie, H.-N. Du, B. Zhong, D. Li, J. Yao
This study shows that tyrosine phosphorylation modulates TRPV2's chemical and thermal sensitivity in macrophages through JAK1 and PTPN1.
bioRxiv · Mar 3, 2022Physiology