P. Provenzano

This study shows that stromal collagen structures in pancreatic ductal adenocarcinoma promote early dissemination from pre-malignant lesions and ongoing invasion, suggesting FAK inhibition or stroma normalization could limit metastasis.

This study engineers T cells to improve 3D migration through tumor microenvironments by manipulating microtubule stability and contractility, showing enhanced migration in 3D matrices and tumors.