Author

P.-L. Loyher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:Drosophila· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

F. Geissmann· 3 shared A. D. Swett· 1 shared A. Hannuna· 1 shared A. I. Domingos· 1 shared A. Stawiarski· 1 shared C. A. P. Sweeney· 1 shared C. E. Gomez-Sanchez· 1 shared C. J. O. O'Brien· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

F. Geissmann

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization

N. Ben-Chetrit, X. Niu, J. Sotelo, A. D. Swett, V. K. Rajasekhar, M. S. Jiao, C. M. Stewart, P. Bhardwaj, S. Kottapalli, S. Ganesan, P.-L. Loyher, C. Potenski, A. Hannuna, K. A. Brown, N. M. Iyengar, , D. A. Landau

This study identifies spatial localization as a key determinant of macrophage heterogeneity and self-renewal in breast cancer, with implications for therapeutic strategies.

bioRxiv · Oct 24, 2023 · PreprintCancer Biology

Distinct adrenal gland macrophages regulate corticosteroid production

C. J. O. O'Brien, D. Sidarta-Oliveira, A. Stawiarski, G. Ratti, P.-L. Loyher, M. Makhlouf, E. H. AbouMoussa, E. Haberman, C. A. P. Sweeney, Y. Mizuno, T. Ishii, T. Hasegawa, E. P. Gomez-Sanchez, C. E. Gomez-Sanchez, S. Gordon, , A. I. Domingos

This study identifies two distinct adrenal macrophage subsets in mice and shows that foamy macrophages regulate corticosteroid production through cholesterol accumulation.

bioRxiv · Sep 5, 2023 · PreprintImmunology

Diet-regulated production of PDGFcc by macrophages controls energy storage

N. Cox, L. Crozet, I. R. Holtman, P.-L. Loyher, T. Lazarov, E. Mass, R. Stanley, C. K. Glass, F. Geissmann

The paper identifies PDGFcc as a diet-regulated macrophage factor that controls energy storage in mammals by acting on adipocytes, independent of inflammation and insulin resistance.

bioRxiv · Jun 15, 2020Immunology