Q. P. Su

This study shows that Escherichia coli lacking RecA rapidly develops beta-lactam resistance through an SOS-independent mechanism involving oxidative stress and DNA repair defects.

This study shows that inducing the bacteriophage PinR in DNA repair-deficient E. coli promotes antibiotic resistance evolution by repressing antioxidative genes and causing ROS bursts.

This paper develops temperature-sensitive nanothermometry probes to measure spatiotemporal thermodynamics of lysosomes and mitochondria in living cells, revealing distinct thermal responses to metabolic perturbations.

This study develops upconversion nanoparticles to monitor mitochondrial temperature dynamics in living cells and shows distinct thermal responses to various stimuli.

The paper visualizes replication foci during S-phase and reveals a CTCF-dependent hierarchical radial propagation pattern that reverses directionality over time.