PathologybioRxiv
Non-canonical Telomerase Reverse Transcriptase Controls Osteogenic Reprogramming of Aortic Valve Cells Through STAT5
R. A. Cuevas, L. Hortells, C. Chu…·C. St. Hilaire
This study identifies TERT's non-canonical role in osteogenic reprogramming of aortic valve cells through STAT5, offering a potential therapeutic target for calcific aortic valve disease.