Author

R. Brocato

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Hooper· 3 shared X. Zeng· 3 shared L. M. Principe· 2 shared S. A. Kwilas· 2 shared B. C. Somerville· 1 shared C. C. Perley· 1 shared D. Gangemi· 1 shared J. Glanville· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersMicrobiology

J. Hooper

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Protective efficacy of a SARS-CoV-2 DNA Vaccine in wild-type and immunosuppressed Syrian hamsters

R. Brocato, S. A. Kwilas, R. K. Kim, X. Zeng, L. M. Principe, J. M. Smith, J. Hooper

This study evaluates a SARS-CoV-2 DNA vaccine in Syrian hamsters, showing it is protective in both healthy and immunosuppressed models.

bioRxiv · Nov 10, 2020Microbiology

Small Animal Jet Injection Technique Results in Enhanced Immunogenicity of Hantavirus DNA Vaccines

R. Brocato, S. A. Kwilas, M. D. Josleyn, S. Long, X. Zeng, C. C. Perley, L. M. Principe, B. C. Somerville, M. V. Cohen, J. Hooper

This study shows that using a jet injection device improves the immunogenicity of hantavirus DNA vaccines in hamsters compared to traditional methods.

bioRxiv · Nov 9, 2020Microbiology

Disruption of Adaptive Immunity Enhances Disease in SARS-CoV-2 Infected Syrian Hamsters

R. Brocato, L. Principe, R. Kim, X. Zeng, J. Williams, Y. Liu, R. Li, J. Smith, J. Golden, D. Gangemi, S. Youssef, Z. Wang, J. Glanville, J. Hooper

This study shows that disrupting adaptive immunity in Syrian hamsters worsens SARS-CoV-2 disease, but a neutralizing antibody reduces infection even in immunosuppressed animals.

bioRxiv · Jun 19, 2020Microbiology

R. Brocato · henhao