Author

R. Calderon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:whole-genome sequencing· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

L. Lecca· 3 shared M. R. Farhat· 3 shared J. Aliaga· 2 shared J. Coit· 2 shared J. Sacchettini· 2 shared L. Freschi· 2 shared M. B. Murray· 2 shared M. Mendoza· 2 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

L. Lecca

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Dual TCR-alpha expression on MAIT cells as a potential confounder of TCR interpretation

S. Suliman, L. Kjer-Nielsen, S. Iwany, K. Lopez, L. Loh, K. Kedzierska, T. A. Ocampo, A. Corbett, J. McCluskey, J. Rossjohn, S. Leon, R. Calderon, L. Lecca, M. B. Murray, B. Moody, I. Van Rhijn

The paper identifies dual TCR-alpha expression on MAIT cells as a confounder in TCR interpretation, showing non-TRAV1-2 TCRs do not bind MR1-5-OP-RU tetramer.

bioRxiv · Mar 25, 2021 · PreprintImmunology

Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology

A. W. Mesman, M. Soto, J. Coit, R. Calderon, J. Aliaga, N. R. Pollock, M. Mendoza, F. M. Mestanza, C. J. Mendoza, M. B. Murray, L. Lecca, R. Holmberg, M. F. Franke

This study evaluates TruTip technology for detecting Mycobacterium tuberculosis in pediatric stool samples, achieving 59% sensitivity and 97% specificity for TB diagnosis.

bioRxiv · Mar 12, 2019Microbiology

Mycobacterium tuberculosis detection from oral swabs with Xpert MTB/RIF ULTRA: A pilot study

A. Mesman, R. Calderon, M. Soto, J. Coit, J. Aliaga, M. Mendoza, M. Franke

This study evaluates the sensitivity of detecting Mycobacterium tuberculosis in oral swabs using Xpert MTB/RIF ULTRA, finding 45% sensitivity and 100% specificity compared to sputum liquid culture.

bioRxiv · Feb 24, 2019Microbiology

Genome wide association with quantitative resistance phenotypes in Mycobacterium tuberculosis reveals novel resistance genes and regulatory regions

M. R. Farhat, L. Freschi, R. Calderon, T. Ioerger, M. Snyder, C. J. Meehan, B. de Jong, L. Rigouts, A. Sloutsky, D. Kaur, S. Sunyaev, D. van Soolingen, J. Shendure, J. Sacchettini, M. Murray

This study identifies novel resistance genes and regulatory regions in Mycobacterium tuberculosis using genome-wide association analysis of drug resistance phenotypes.

bioRxiv · Oct 1, 2018Evolutionary Biology

Rifampicin and rifabutin resistance in 1000 Mycobacterium tuberculosis clinical isolates

M. R. Farhat, J. Sixsmith, R. Calderon, N. Hicks, S. Fortune, M. Murray

The paper investigates rifamycin resistance in Mycobacterium tuberculosis isolates, finding that the D435V rpoB mutation increases IC50 for both rifampicin and rifabutin, suggesting the need to revise RFB testing concentrations.

bioRxiv · Sep 25, 2018Evolutionary Biology

Genotypic clustering does not imply recent tuberculosis transmission in a high prevalence setting: A genomic epidemiology study in Lima, Peru

A. Dixit, L. Freschi, R. Vargas, R. Calderon, J. Sacchettini, F. Drobniewski, J. T. Galea, C. Contreras, R. Yataco, Z. Zhang, L. Lecca, S.-O. Kolokotronis, B. Mathema, M. R. Farhat

This study uses genomic data to show that TB clusters identified by traditional methods may persist for decades, and WGS reveals genetic factors that may enhance transmissibility.

bioRxiv · Sep 16, 2018Microbiology