Author

J. McCluskey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. J. Corbett· 2 shared B. S. Meehan· 2 shared K. Kedzierska· 2 shared L. Kostenko· 2 shared L. Loh· 2 shared P. Klenerman· 2 shared T. J. Pediongco· 2 shared Z. Chen· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. J. Corbett

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Author profile →

3 papers

Recent·Most cited

Dual TCR-alpha expression on MAIT cells as a potential confounder of TCR interpretation

S. Suliman, L. Kjer-Nielsen, S. Iwany, K. Lopez, L. Loh, K. Kedzierska, T. A. Ocampo, A. Corbett, J. McCluskey, J. Rossjohn, S. Leon, R. Calderon, L. Lecca, M. B. Murray, B. Moody, I. Van Rhijn

The paper identifies dual TCR-alpha expression on MAIT cells as a confounder in TCR interpretation, showing non-TRAV1-2 TCRs do not bind MR1-5-OP-RU tetramer.

bioRxiv · Mar 25, 2021 · PreprintImmunology

Activation and in vivo evolution of the MAIT cell transcriptome in mice and humans reveals diverse functionality

T. S. C. Hinks, E. Marchi, M. Jabeen, M. Olshansky, A. Kurioka, T. J. Pediongco, B. S. Meehan, L. Kostenko, S. J. Turner, A. J. Corbett, Z. Chen, P. Klenerman, J. McCluskey

The paper defines the transcriptome of activated MAIT cells in mice and humans and shows how it changes during infection phases, revealing a tissue repair phenotype.

bioRxiv · Dec 9, 2018 · PreprintImmunology

MAIT cells contribute to protection against lethal influenza infection in vivo

B. van Wilgenburg, L. Loh, Z. Chen, T. J. Pediongco, H. Wang, M. Shi, Z. Zhao, M. Koutsakos, S. Nussing, S. Sant, Z. Wang, C. D'Souza, C. F. Almeida, L. Kostenko, S. B. Eckle, , T. Hinks

This study shows MAIT cells protect against lethal influenza infection by accumulating and being activated early, with their absence increasing mortality in mice.

bioRxiv · Mar 23, 2018Immunology