Pharmacology & ToxicologybioRxivPreprint
Cebranopadol, a novel long-acting opioid agonist with low abuse liability, to treat opioid use disorder: Preclinical evidence of efficacy
V. Lunerti, Q. Shen, H. Li…·R. Ciccocioppo
This study evaluates cebranopadol's efficacy and abuse liability in treating opioid use disorder using rat models, showing reduced self-administration and stress-induced reinstatement compared to heroin.
DOI 10.1101/2023.07.21.550008