Author

R. Costa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

D. Bojkova· 2 shared J. Cinatl· 2 shared M. Michaelis· 2 shared B. Bilen· 1 shared C. Schneider· 1 shared D. Thomas· 1 shared E. Karimi· 1 shared F. Rothweiler· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

D. Bojkova

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells

T. Rothenburger, D. Thomas, Y. Schreiber, P. R. Wratil, T. Pflantz, K. Knecht, K. Digianantonio, J. Temple, C. Schneider, H.-M. Baldauf, K.-M. McLaughlin, F. Rothweiler, B. Bilen, S. Farmand, D. Bojkova, , J. Cinatl

This study identifies intrinsic and acquired resistance mechanisms to CNDAC and related nucleoside analogues in AML cells, showing distinct roles of SAMHD1 and DCK.

bioRxiv · Jul 19, 2021Pharmacology & Toxicology

Expression of Castanea crenata Allene Oxide Synthase in Arabidopsis Improves the Defense to Phytophthora cinnamomi

S. M. Serrazina, H. Machado, R. Costa, P. Duque, R. M. Malho

Heterologous expression of the Castanea crenata allene oxide synthase gene in Arabidopsis thaliana improves the defense response to the pathogen Phytophthora cinnamomi.

bioRxiv · Oct 9, 2020Plant Biology

Targeting pentose phosphate pathway for SARS-CoV-2 therapy

D. Bojkova, R. Costa, M. Bechtel, S. Ciesek, M. Michaelis, J. Cinatl

This study identifies the pentose phosphate pathway as a target for SARS-CoV-2 therapy and shows that inhibiting it with benfooxythiamine reduces viral replication.

bioRxiv · Aug 19, 2020Microbiology

Isolation and genome sequencing of 14 Spongia sp. bacterial associates expands the taxonomic and functional breadth of the cultivatable marine sponge microbiome

E. Karimi, R. Costa

The paper isolates and sequences 14 bacterial strains from a marine sponge, revealing new genera and functional genes related to symbiosis and secondary metabolites.

bioRxiv · Mar 20, 2020 · PreprintMicrobiology