Author

J. Temple

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. Bibik· 2 shared J. Weissman· 2 shared P. Neofotis· 2 shared Y. Xiong· 2 shared A. Engelman· 1 shared A. Withrow· 1 shared B. Bilen· 1 shared B. F. Lucker· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersEvolutionary Biology

J. Bibik

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Differences between intrinsic and acquired nucleoside analogue resistance in acute myeloid leukaemia cells

T. Rothenburger, D. Thomas, Y. Schreiber, P. R. Wratil, T. Pflantz, K. Knecht, K. Digianantonio, J. Temple, C. Schneider, H.-M. Baldauf, K.-M. McLaughlin, F. Rothweiler, B. Bilen, S. Farmand, D. Bojkova, , J. Cinatl

This study identifies intrinsic and acquired resistance mechanisms to CNDAC and related nucleoside analogues in AML cells, showing distinct roles of SAMHD1 and DCK.

bioRxiv · Jul 19, 2021Pharmacology & Toxicology

Selection-Enriched Genomic Loci (SEGL) Reveals Genetic Loci for Environmental Adaptation and Photosynthetic Productivity in Chlamydomonas reinhardtii.

B. F. Lucker, N. Panchy, J. Temple, U. Benning, J. Bibik, P. Neofotis, J. Weissman, I. Baxter, S.-H. Shu, D. Kramer

This paper develops a method to identify genetic loci associated with environmental adaptation and photosynthetic productivity in algae by selecting high-performing strains under various conditions.

bioRxiv · Jul 6, 2021Evolutionary Biology

The Induction of Pyrenoid Synthesis by Hyperoxia and its Implications for the Natural Diversity of Photosynthetic Responses in Chlamydomonas

P. Neofotis, J. Temple, O. Tessmer, J. Bibik, N. Norris, E. Poliner, B. Lucker, S. Wijetilleke, A. Withrow, B. Sears, G. Mogos, M. Frame, D. Hall, J. Weissman, D. M. Kramer

This study shows that hyperoxia induces pyrenoid formation in Chlamydomonas reinhardtii, suggesting H2O2 as a signaling molecule and linking it to genetic variation in hyperoxia tolerance and pyrenoid morphology.

bioRxiv · Mar 10, 2021Plant Biology

A DNA-origami nuclear pore mimic reveals nuclear entry mechanisms of HIV-1 capsid

Q. Shen, C. Xu, S. Jang, Q. Xiong, S. Devarkar, T. Tian, G. Bedwell, T. Tripler, Y. Hu, S. Yuan, J. Temple, J. Shi, C. Aiken, A. Engelman, J. R. Perilla, , Y. Xiong

This study uses DNA-origami NPC mimics to show HIV-1 capsid uses a trimeric interface and RRR motif to pass through nuclear pores, bypassing the FG motif of NUP153.

bioRxiv · Aug 10, 2020 · PreprintMicrobiology